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/* |
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* Created on Aug 30, 2005 |
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*/ |
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package org.tigr.microarray.mev.cluster.gui.impl.bridge; |
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|
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import java.io.File; |
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import java.io.FileWriter; |
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import java.io.IOException; |
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import java.text.DecimalFormat; |
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import java.util.StringTokenizer; |
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import java.util.Vector; |
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|
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import javax.swing.JFileChooser; |
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import javax.swing.JFrame; |
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import javax.swing.JOptionPane; |
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import javax.swing.tree.DefaultMutableTreeNode; |
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|
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import org.tigr.microarray.mev.TMEV; |
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import org.tigr.microarray.mev.cluster.algorithm.AlgorithmException; |
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import org.tigr.microarray.mev.cluster.gui.Experiment; |
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import org.tigr.microarray.mev.cluster.gui.IClusterGUI; |
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import org.tigr.microarray.mev.cluster.gui.IData; |
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import org.tigr.microarray.mev.cluster.gui.IFramework; |
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import org.tigr.microarray.mev.cluster.gui.IViewer; |
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import org.tigr.microarray.mev.cluster.gui.LeafInfo; |
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import org.tigr.microarray.mev.cluster.gui.helpers.CentroidUserObject; |
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import org.tigr.microarray.mev.cluster.gui.helpers.ClusterTableViewer; |
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import org.tigr.microarray.mev.cluster.gui.helpers.ExperimentViewer; |
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import org.tigr.microarray.mev.r.RDataFormatter; |
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import org.tigr.microarray.mev.r.RHyb; |
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import org.tigr.microarray.mev.r.RHybSet; |
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import org.tigr.microarray.mev.r.RProgress; |
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import org.tigr.microarray.mev.r.RamaTextFileFilter; |
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import org.tigr.microarray.mev.r.Rconnection; |
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import org.tigr.microarray.mev.r.RconnectionManager; |
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|
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/** |
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* @author iVu |
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*/ |
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public class BridgeGUI implements IClusterGUI { |
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public static String TAB = "\t"; |
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public static String END_LINE = "\r\n"; |
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public static String R_VECTOR_NAME = "bData"; |
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|
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private double threshold; |
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|
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private RProgress progress; |
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|
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//Labels for the Y Axis of Expression Graphs |
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private String yNum = "IntB"; |
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private String yDenom = "IntA"; |
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private String dataPath; |
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|
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|
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|
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public DefaultMutableTreeNode execute(IFramework framework) |
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throws AlgorithmException { |
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this.dataPath = TMEV.getDataPath(); |
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DefaultMutableTreeNode root = new DefaultMutableTreeNode( "BRIDGE" ); |
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IData data = framework.getData(); |
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Experiment exp = data.getExperiment(); |
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int dataType = data.getDataType(); |
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|
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if( dataType == IData.DATA_TYPE_RATIO_ONLY ) { |
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this.error( "bridge does not work on Ratio data.\nIt only works with Intensity data." ); |
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return null; |
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} else if( dataType == IData.DATA_TYPE_AFFY_MEAN ) { |
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this.error( "bridge does not work on Affy Mean data.\nIt only works with Affy Absolute data." ); |
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return null; |
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} else if( dataType == IData.DATA_TYPE_AFFY_MEDIAN ) { |
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this.error( "bridge does not work on Affy Median data.\nIt only works with Affy Absolute data." ); |
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return null; |
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} else if( dataType == IData.DATA_TYPE_AFFY_REF ) { |
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this.error( "bridge does not work on Affy Reference data.\nIt only works with Affy Absolute data." ); |
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return null; |
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} else { |
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//data is either Affy or 2 color (both colors present as IA & IB rather than just a ratio) |
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|
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//first check to see if there is enough data to run (4 affy or 2 2Color) |
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int minFeatures = 4; |
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if( dataType == IData.DATA_TYPE_TWO_INTENSITY ) { |
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minFeatures = 2; |
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} |
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if( data.getFeaturesCount() < minFeatures ) { |
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//not enough |
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this.error( "bridge requires a minimum of 2 replicates per treatment type" ); |
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return null; |
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} else { |
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//now prescreen for NaN |
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if( this.dataHasNulls( data ) ) { |
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//problem |
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this.error( "Your dataset has null values in it.\r\n" + |
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"It will not work with bridge.\r\n" + |
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"You may consider removing genes where null values appear." ); |
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return null; |
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} else { |
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BridgeResult br = this.bridgify( framework, data, data.getDataType() ); |
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if( br != null ) { |
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this.createExpressionImages( root, data, br, this.yNum, this.yDenom ); |
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|
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//kill the progress bar if it is lingering (if user cancels) |
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if( this.progress != null ) { |
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this.progress.kill(); |
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} |
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|
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return root; |
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} else { |
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//deal with null result |
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|
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//kill the progress bar if it is lingering (if user cancels) |
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if( this.progress != null ) { |
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this.progress.kill(); |
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} |
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|
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return null; |
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} |
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} |
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} |
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}//else |
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}//constructor |
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|
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|
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/** |
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* Prescreening method to look for NaN values in the dataset. |
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* @param data |
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* @return |
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*/ |
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private boolean dataHasNulls( IData data ) { |
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boolean toReturn = false; |
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|
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Experiment exp = data.getExperiment(); |
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|
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float[][] matrix = exp.getValues(); |
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for( int i = 0; i < matrix.length; i ++ ) { |
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for( int j = 0; j < matrix[ i ].length; j ++ ) { |
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float fValue = matrix[ i ][ j ]; |
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|
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//Float.compare( fValue, Float.NaN ); |
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if( Float.isNaN( fValue ) ) { |
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//System.out.println( i + "," + j + " is NaN" ); |
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toReturn = true; |
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break; |
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} |
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} |
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} |
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|
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return toReturn; |
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}//datahasNulls() |
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|
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|
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/** |
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* |
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* @param framework |
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* @param data |
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* @param dataType |
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* @return |
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*/ |
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private BridgeResult bridgify( IFramework framework, IData data, int dataType ) { |
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BridgeResult toReturn = null; |
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|
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//we need to gather up the data and format it for RAMA |
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String[] hybNames = new String[ data.getFeaturesCount() ]; |
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for( int h = 0; h < hybNames.length; h ++ ) { |
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hybNames[ h ] = data.getFullSampleName( h ); |
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} |
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|
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//have user label loaded data |
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BridgeInitDialog initDialog = new BridgeInitDialog( framework.getFrame(), |
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hybNames, dataType ); |
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if( initDialog.showModal() == JOptionPane.OK_OPTION ) { |
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//get the advanced parameters |
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int B = initDialog.getNumIter(); |
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int minIter = initDialog.getBurnIn(); |
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this.threshold = initDialog.getThreshold(); |
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String sConnPort = initDialog.getSelectedConnString(); |
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int iPort = this.parseIPort( sConnPort ); |
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String sConn = this.parseSPort( sConnPort ); |
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this.setYNum( initDialog.getYNum() ); |
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this.setYDenom( initDialog.getYDen() ); |
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|
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//Object to format MeV-IData structure into R data String |
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RDataFormatter rDataFormatter = new RDataFormatter( data ); |
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RHybSet bhs = initDialog.getBridgeHybSet(); |
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|
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//data that characterizes loaded data |
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String sData; // |
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int iGene; //# genes |
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int iHybKount; //# hybs |
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int iColorKount; //# data points for both colors/all hybs (#hybs * 2) |
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int iTwo; //start index of 2nd color |
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int nbCol1; //# of hybs in 1st color state |
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|
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if( bhs.isFlip() ) { //dealing with a dye swap experiment |
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//Split into color state |
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Vector vTreatCy3 = this.getVRamaHybTreatCy3( bhs.getVRamaHyb() ); |
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Vector vTreatCy5 = this.getVRamaHybTreatCy5( bhs.getVRamaHyb() ); |
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|
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sData = rDataFormatter.rSwapString( BridgeGUI.R_VECTOR_NAME, vTreatCy3, vTreatCy5 ); |
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iGene = data.getExperiment().getNumberOfGenes(); |
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nbCol1 = vTreatCy3.size(); |
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iHybKount = vTreatCy3.size() + vTreatCy5.size(); |
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iColorKount = iHybKount * 2; |
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iTwo = iHybKount + 1; |
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} else { //not dye swap |
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sData = rDataFormatter.rNonSwapString( BridgeGUI.R_VECTOR_NAME, bhs.getVRamaHyb() ); |
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iGene = data.getExperiment().getNumberOfGenes(); |
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nbCol1 = 0; |
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iHybKount = bhs.getVRamaHyb().size(); |
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iColorKount = iHybKount * 2; |
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iTwo = iHybKount + 1; |
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}//end rhs.isFlip() else |
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|
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26 Feb 07 |
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//display an inderterminate progress bar so user knows it's working |
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double dTimePerCalc = 0.000015d; |
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double dIntensityKount = ( double ) iGene * ( double ) iHybKount; |
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double dTotalTime = dIntensityKount * dTimePerCalc * B; |
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double dMinutes = dTotalTime / 60d; |
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DecimalFormat df = new DecimalFormat( "###.#" ); |
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String estTime = df.format( dMinutes ); |
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26 Feb 07 |
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String message = "It may take as long as " + estTime + " minutes with your data set"; |
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this.progress = new RProgress( ( JFrame ) framework.getFrame(), message ); |
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|
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26 Feb 07 |
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//get a connection |
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RconnectionManager rcMan = new RconnectionManager( |
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26 Feb 07 |
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framework.getFrame(), sConn, iPort ); |
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Rconnection rc = rcMan.getConnection(); |
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|
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26 Feb 07 |
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//don't continue if we can't get a connection |
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if( rc != null ) { |
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26 Feb 07 |
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//create R command strings |
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String sClear = "rm(" + BridgeGUI.R_VECTOR_NAME + ")"; |
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String sLibrary = "library(bridge)"; |
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String sReform = "dim(" + BridgeGUI.R_VECTOR_NAME + ") <- c(" + iGene + "," + iColorKount + ")"; |
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String sMcMc = this.createMcMc( iGene, iHybKount, iHybKount, iTwo, iColorKount, B, minIter, dataType ); |
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String sAvg1 = "gamma1<-mat.mean(bridge." + BridgeGUI.R_VECTOR_NAME + "$gamma1)[,1]"; |
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String sAvg2 = "gamma2<-mat.mean(bridge." + BridgeGUI.R_VECTOR_NAME + "$gamma2)[,1]"; |
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String sPostP = "bridge." + BridgeGUI.R_VECTOR_NAME + "$post.p"; |
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|
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final BridgeWorker bThread = new BridgeWorker( rc, sClear, |
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sLibrary, sData, sReform, sMcMc, sAvg1, sAvg2, |
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sPostP, this.threshold, progress ); |
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bThread.start(); |
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|
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//wait to allow the worker to finish before proceeding |
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while( !bThread.isDone() ) { |
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try { |
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Thread.sleep( 10000 ); |
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} catch( InterruptedException e ) { |
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e.printStackTrace(); |
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} |
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}//while() |
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|
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//get the result |
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toReturn = bThread.getResult(); |
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|
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if( toReturn != null ) { |
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//need to know the gene annotation data |
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String[] geneNames = new String[ iGene ]; |
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for( int g = 0; g < iGene; g ++ ) { |
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String name = data.getGeneName( g ); |
2 |
26 Feb 07 |
jari |
261 |
if( name == null ) { |
2 |
26 Feb 07 |
jari |
262 |
name = Integer.toString( g + 1 ); |
2 |
26 Feb 07 |
jari |
263 |
} |
2 |
26 Feb 07 |
jari |
264 |
geneNames[ g ] = name; |
2 |
26 Feb 07 |
jari |
265 |
}//g |
2 |
26 Feb 07 |
jari |
266 |
|
2 |
26 Feb 07 |
jari |
//store these arrays in BridgeResult object |
2 |
26 Feb 07 |
jari |
//toReturn = new BridgeResult( gamma1, gamma2, pprob, this.threshold ); |
2 |
26 Feb 07 |
jari |
269 |
toReturn.setGeneNames( geneNames ); |
2 |
26 Feb 07 |
jari |
270 |
|
2 |
26 Feb 07 |
jari |
//seemed to have worked so save the connection strings |
2 |
26 Feb 07 |
jari |
272 |
if( initDialog.connAdded() ) { |
2 |
26 Feb 07 |
jari |
273 |
TMEV.updateRPath( initDialog.getRPathToWrite() ); |
2 |
26 Feb 07 |
jari |
274 |
} |
2 |
26 Feb 07 |
jari |
275 |
} else { |
2 |
26 Feb 07 |
jari |
276 |
System.out.println("Null Results from BridgeWorker" ); |
2 |
26 Feb 07 |
jari |
277 |
} |
2 |
26 Feb 07 |
jari |
278 |
} else { //end if( rc != null ) |
2 |
26 Feb 07 |
jari |
//deal with null connection, kill everything |
2 |
26 Feb 07 |
jari |
280 |
this.error( "Couldn't establish an Rserve Connection" ); |
2 |
26 Feb 07 |
jari |
281 |
} |
2 |
26 Feb 07 |
jari |
282 |
}//end OK_OPTION |
2 |
26 Feb 07 |
jari |
283 |
|
2 |
26 Feb 07 |
jari |
284 |
return toReturn; |
2 |
26 Feb 07 |
jari |
285 |
}//twoIntensity() |
2 |
26 Feb 07 |
jari |
286 |
|
2 |
26 Feb 07 |
jari |
287 |
|
2 |
26 Feb 07 |
jari |
288 |
|
2 |
26 Feb 07 |
jari |
289 |
/** |
2 |
26 Feb 07 |
jari |
* Creates a Vector of RHybs where: treated-Cy3 | control-Cy5 |
2 |
26 Feb 07 |
jari |
* @return |
2 |
26 Feb 07 |
jari |
292 |
*/ |
2 |
26 Feb 07 |
jari |
293 |
private Vector getVRamaHybTreatCy3( Vector ramaHybs ) { |
2 |
26 Feb 07 |
jari |
294 |
Vector vReturn = new Vector(); |
2 |
26 Feb 07 |
jari |
295 |
|
2 |
26 Feb 07 |
jari |
296 |
for( int h = 0; h < ramaHybs.size(); h ++ ) { |
2 |
26 Feb 07 |
jari |
297 |
RHyb hyb = ( RHyb ) ramaHybs.elementAt( h ); |
2 |
26 Feb 07 |
jari |
298 |
if( ! hyb.controlCy3() ) { |
2 |
26 Feb 07 |
jari |
299 |
vReturn.add( hyb ); |
2 |
26 Feb 07 |
jari |
300 |
} |
2 |
26 Feb 07 |
jari |
301 |
} |
2 |
26 Feb 07 |
jari |
302 |
|
2 |
26 Feb 07 |
jari |
303 |
return vReturn; |
2 |
26 Feb 07 |
jari |
304 |
} |
2 |
26 Feb 07 |
jari |
305 |
/** |
2 |
26 Feb 07 |
jari |
* Creates a Vector of RHybs where: control-Cy3 | treated-Cy5 |
2 |
26 Feb 07 |
jari |
* @return |
2 |
26 Feb 07 |
jari |
308 |
*/ |
2 |
26 Feb 07 |
jari |
309 |
private Vector getVRamaHybTreatCy5( Vector ramaHybs ) { |
2 |
26 Feb 07 |
jari |
310 |
Vector vReturn = new Vector(); |
2 |
26 Feb 07 |
jari |
311 |
|
2 |
26 Feb 07 |
jari |
312 |
for( int h = 0; h < ramaHybs.size(); h ++ ) { |
2 |
26 Feb 07 |
jari |
313 |
RHyb hyb = ( RHyb ) ramaHybs.elementAt( h ); |
2 |
26 Feb 07 |
jari |
314 |
if( hyb.controlCy3() ) { |
2 |
26 Feb 07 |
jari |
315 |
vReturn.add( hyb ); |
2 |
26 Feb 07 |
jari |
316 |
} |
2 |
26 Feb 07 |
jari |
317 |
} |
2 |
26 Feb 07 |
jari |
318 |
|
2 |
26 Feb 07 |
jari |
319 |
return vReturn; |
2 |
26 Feb 07 |
jari |
320 |
}// |
2 |
26 Feb 07 |
jari |
321 |
|
2 |
26 Feb 07 |
jari |
322 |
|
2 |
26 Feb 07 |
jari |
323 |
/** |
2 |
26 Feb 07 |
jari |
324 |
* |
2 |
26 Feb 07 |
jari |
* @param iGene |
2 |
26 Feb 07 |
jari |
* @param iHybKount |
2 |
26 Feb 07 |
jari |
* @param iOne |
2 |
26 Feb 07 |
jari |
* @param iTwo |
2 |
26 Feb 07 |
jari |
* @param iColorKount |
2 |
26 Feb 07 |
jari |
* @param B |
2 |
26 Feb 07 |
jari |
* @param minIter |
2 |
26 Feb 07 |
jari |
* @param dataType |
2 |
26 Feb 07 |
jari |
* @return |
2 |
26 Feb 07 |
jari |
334 |
*/ |
2 |
26 Feb 07 |
jari |
335 |
private String createMcMc( int iGene, int iHybKount, int iOne, int iTwo, |
2 |
26 Feb 07 |
jari |
336 |
int iColorKount, int B, int minIter, int dataType ) { |
2 |
26 Feb 07 |
jari |
337 |
StringBuffer sb = new StringBuffer(); |
2 |
26 Feb 07 |
jari |
338 |
sb.append( "bridge." ); |
2 |
26 Feb 07 |
jari |
339 |
sb.append( BridgeGUI.R_VECTOR_NAME ); |
2 |
26 Feb 07 |
jari |
340 |
sb.append( "<- bridge.2samples( " ); |
2 |
26 Feb 07 |
jari |
341 |
sb.append( BridgeGUI.R_VECTOR_NAME ); |
2 |
26 Feb 07 |
jari |
342 |
sb.append( "[ 1:" ); |
2 |
26 Feb 07 |
jari |
343 |
sb.append( iGene ); |
2 |
26 Feb 07 |
jari |
344 |
sb.append( " , c( 1:" ); |
2 |
26 Feb 07 |
jari |
345 |
sb.append( iHybKount ); |
2 |
26 Feb 07 |
jari |
346 |
sb.append( " )], " + BridgeGUI.R_VECTOR_NAME + "[ 1:" ); |
2 |
26 Feb 07 |
jari |
347 |
sb.append( iGene ); |
2 |
26 Feb 07 |
jari |
348 |
sb.append( ", c( " ); |
2 |
26 Feb 07 |
jari |
349 |
sb.append( iTwo ); |
2 |
26 Feb 07 |
jari |
350 |
sb.append( ":" ); |
2 |
26 Feb 07 |
jari |
351 |
sb.append( iColorKount ); |
2 |
26 Feb 07 |
jari |
352 |
sb.append( " )], B = " ); |
2 |
26 Feb 07 |
jari |
353 |
sb.append( B ); |
2 |
26 Feb 07 |
jari |
354 |
sb.append( ", min.iter = " ); |
2 |
26 Feb 07 |
jari |
355 |
sb.append( minIter ); |
2 |
26 Feb 07 |
jari |
356 |
sb.append( ", batch = 1, mcmc.obj = NULL, affy = " ); |
2 |
26 Feb 07 |
jari |
357 |
if( dataType == IData.DATA_TYPE_TWO_INTENSITY ) { |
2 |
26 Feb 07 |
jari |
358 |
sb.append( "FALSE" ); |
2 |
26 Feb 07 |
jari |
359 |
} else { |
2 |
26 Feb 07 |
jari |
360 |
sb.append( "TRUE" ); |
2 |
26 Feb 07 |
jari |
361 |
} |
2 |
26 Feb 07 |
jari |
362 |
sb.append( ", verbose = TRUE )" ); |
2 |
26 Feb 07 |
jari |
//System.out.println(sb.toString()); |
2 |
26 Feb 07 |
jari |
364 |
return sb.toString(); |
2 |
26 Feb 07 |
jari |
//return "mcmc.hiv <- bridge.2samples( hiv[ 1:10 , c( 1:2 )], hiv[ 1:10, c( 2:2 )], B = 21000, min.iter = 1000, batch = 1, mcmc.obj = NULL, affy = FALSE, verbose = TRUE )"; |
2 |
26 Feb 07 |
jari |
366 |
}//createMcMc() |
2 |
26 Feb 07 |
jari |
367 |
|
2 |
26 Feb 07 |
jari |
368 |
|
2 |
26 Feb 07 |
jari |
369 |
/** |
2 |
26 Feb 07 |
jari |
* Creates Heat Maps of Significant and Non Significant genes |
2 |
26 Feb 07 |
jari |
* @param root |
2 |
26 Feb 07 |
jari |
* @param data |
2 |
26 Feb 07 |
jari |
* @param br |
2 |
26 Feb 07 |
jari |
* @return |
2 |
26 Feb 07 |
jari |
375 |
*/ |
2 |
26 Feb 07 |
jari |
376 |
private void createExpressionImages( DefaultMutableTreeNode root, |
2 |
26 Feb 07 |
jari |
377 |
IData data, BridgeResult br, String yNum, String yDenom ) { |
2 |
26 Feb 07 |
jari |
378 |
|
2 |
26 Feb 07 |
jari |
379 |
DefaultMutableTreeNode expViewerNode = new DefaultMutableTreeNode( |
2 |
26 Feb 07 |
jari |
380 |
"Expression Images" ); |
2 |
26 Feb 07 |
jari |
381 |
DefaultMutableTreeNode cenViewerNode = new DefaultMutableTreeNode( |
2 |
26 Feb 07 |
jari |
382 |
"Expression Graphs" ); |
2 |
26 Feb 07 |
jari |
383 |
DefaultMutableTreeNode tableNode = new DefaultMutableTreeNode("Table Views"); |
2 |
26 Feb 07 |
jari |
384 |
|
2 |
26 Feb 07 |
jari |
385 |
Experiment exp = data.getExperiment(); |
2 |
26 Feb 07 |
jari |
386 |
|
2 |
26 Feb 07 |
jari |
//create new clusters for sig/nonsig gene sets |
2 |
26 Feb 07 |
jari |
388 |
int[][] newClusters = this.createClusters( br ); |
2 |
26 Feb 07 |
jari |
389 |
|
2 |
26 Feb 07 |
jari |
//create heat map viewers for sig/nonsig gene sets |
2 |
26 Feb 07 |
jari |
391 |
ExperimentViewer expViewer = new ExperimentViewer( exp, newClusters ); |
2 |
26 Feb 07 |
jari |
392 |
expViewerNode.add(new DefaultMutableTreeNode(new LeafInfo("Significant Genes ", expViewer, new Integer(0)))); |
2 |
26 Feb 07 |
jari |
393 |
expViewerNode.add(new DefaultMutableTreeNode(new LeafInfo("Non-significant Genes ", expViewer, new Integer(1)))); |
2 |
26 Feb 07 |
jari |
394 |
|
2 |
26 Feb 07 |
jari |
//create centroid viewers for sig/nonsig gene sets |
2 |
26 Feb 07 |
jari |
396 |
BridgeCentroidViewer centViewer = new BridgeCentroidViewer( exp, newClusters, yNum, yDenom ); |
2 |
26 Feb 07 |
jari |
397 |
centViewer.setMeans( this.calculateMeans( exp, br ) ); |
2 |
26 Feb 07 |
jari |
398 |
cenViewerNode.add(new DefaultMutableTreeNode(new LeafInfo( |
2 |
26 Feb 07 |
jari |
399 |
"Significant Genes ", centViewer, new CentroidUserObject( 0, |
2 |
26 Feb 07 |
jari |
400 |
CentroidUserObject.VALUES_MODE)))); |
2 |
26 Feb 07 |
jari |
401 |
cenViewerNode.add(new DefaultMutableTreeNode(new LeafInfo( |
2 |
26 Feb 07 |
jari |
402 |
"Non-significant Genes ", centViewer, new CentroidUserObject( 1, |
2 |
26 Feb 07 |
jari |
403 |
CentroidUserObject.VALUES_MODE)))); |
2 |
26 Feb 07 |
jari |
404 |
// |
2 |
26 Feb 07 |
jari |
405 |
String[] headers = br.getHeaders(); |
2 |
26 Feb 07 |
jari |
406 |
String[][] auxData = br.getAuxData(); |
2 |
26 Feb 07 |
jari |
407 |
IViewer tabViewer = new ClusterTableViewer( exp, newClusters, data, headers, auxData ); |
2 |
26 Feb 07 |
jari |
408 |
tableNode.add(new DefaultMutableTreeNode(new LeafInfo("Significant Genes ", tabViewer, new Integer(0)))); |
2 |
26 Feb 07 |
jari |
409 |
tableNode.add(new DefaultMutableTreeNode(new LeafInfo("Non-significant Genes ", tabViewer, new Integer(1)))); |
2 |
26 Feb 07 |
jari |
410 |
|
2 |
26 Feb 07 |
jari |
411 |
root.add( expViewerNode ); |
2 |
26 Feb 07 |
jari |
412 |
root.add( cenViewerNode ); |
2 |
26 Feb 07 |
jari |
413 |
root.add( tableNode ); |
2 |
26 Feb 07 |
jari |
414 |
}//createViews() |
2 |
26 Feb 07 |
jari |
415 |
|
2 |
26 Feb 07 |
jari |
416 |
|
2 |
26 Feb 07 |
jari |
417 |
/** |
2 |
26 Feb 07 |
jari |
* clusters = int[ dataset index ][ row index ] |
2 |
26 Feb 07 |
jari |
* @param br |
2 |
26 Feb 07 |
jari |
* @return |
2 |
26 Feb 07 |
jari |
421 |
*/ |
2 |
26 Feb 07 |
jari |
422 |
private int[][] createClusters( BridgeResult br ) { |
2 |
26 Feb 07 |
jari |
423 |
int[][] toReturn = new int[ 2 ][]; |
2 |
26 Feb 07 |
jari |
424 |
toReturn[ 0 ] = br.getSigIndices(); |
2 |
26 Feb 07 |
jari |
425 |
toReturn[ 1 ] = br.getNonIndices(); |
2 |
26 Feb 07 |
jari |
426 |
|
2 |
26 Feb 07 |
jari |
427 |
return toReturn; |
2 |
26 Feb 07 |
jari |
428 |
}//createClusters() |
2 |
26 Feb 07 |
jari |
429 |
|
2 |
26 Feb 07 |
jari |
430 |
|
2 |
26 Feb 07 |
jari |
431 |
/** |
2 |
26 Feb 07 |
jari |
432 |
* |
2 |
26 Feb 07 |
jari |
* @param exp |
2 |
26 Feb 07 |
jari |
* @return |
2 |
26 Feb 07 |
jari |
435 |
*/ |
2 |
26 Feb 07 |
jari |
436 |
private float[][] calculateMeans( Experiment exp, BridgeResult br ) { |
2 |
26 Feb 07 |
jari |
437 |
int[] sigIndices = br.getSigIndices(); |
2 |
26 Feb 07 |
jari |
438 |
int[] nonIndices = br.getNonIndices(); |
2 |
26 Feb 07 |
jari |
439 |
float[][] ratios = exp.getValues(); |
2 |
26 Feb 07 |
jari |
440 |
float[][] toReturn = new float[ 2 ][ ratios[ 0 ].length ]; |
2 |
26 Feb 07 |
jari |
441 |
|
2 |
26 Feb 07 |
jari |
//loop through the hybs |
2 |
26 Feb 07 |
jari |
443 |
for( int h = 0; h < ratios[ 0 ].length; h ++ ) { |
2 |
26 Feb 07 |
jari |
//avg sig genes for each hyb |
2 |
26 Feb 07 |
jari |
445 |
float sigTotal = 0; |
2 |
26 Feb 07 |
jari |
446 |
float nonTotal = 0; |
2 |
26 Feb 07 |
jari |
447 |
|
2 |
26 Feb 07 |
jari |
//loop through the sig genes |
2 |
26 Feb 07 |
jari |
449 |
for( int i = 0; i < sigIndices.length; i ++ ) { |
2 |
26 Feb 07 |
jari |
450 |
sigTotal = sigTotal + ratios[ sigIndices[ i ] ][ h ]; |
2 |
26 Feb 07 |
jari |
451 |
}//i |
2 |
26 Feb 07 |
jari |
452 |
|
2 |
26 Feb 07 |
jari |
453 |
float sigAvg = sigTotal / ( float ) sigIndices.length; |
2 |
26 Feb 07 |
jari |
454 |
toReturn[ 0 ][ h ] = sigAvg; |
2 |
26 Feb 07 |
jari |
455 |
|
2 |
26 Feb 07 |
jari |
//loop through the nonsig genes |
2 |
26 Feb 07 |
jari |
457 |
for( int i = 0; i < nonIndices.length; i ++ ) { |
2 |
26 Feb 07 |
jari |
458 |
nonTotal = nonTotal + ratios[ nonIndices[ i ] ][ h ]; |
2 |
26 Feb 07 |
jari |
459 |
} |
2 |
26 Feb 07 |
jari |
460 |
|
2 |
26 Feb 07 |
jari |
461 |
float nonAvg = nonTotal / ( float ) nonIndices.length; |
2 |
26 Feb 07 |
jari |
462 |
toReturn [ 1 ][ h ] = nonAvg; |
2 |
26 Feb 07 |
jari |
463 |
}//h |
2 |
26 Feb 07 |
jari |
464 |
|
2 |
26 Feb 07 |
jari |
465 |
return toReturn; |
2 |
26 Feb 07 |
jari |
466 |
}//calculateMeans() |
2 |
26 Feb 07 |
jari |
467 |
|
2 |
26 Feb 07 |
jari |
468 |
|
2 |
26 Feb 07 |
jari |
469 |
/** |
2 |
26 Feb 07 |
jari |
470 |
* |
2 |
26 Feb 07 |
jari |
* @param gamma1 |
2 |
26 Feb 07 |
jari |
* @param gamma2 |
2 |
26 Feb 07 |
jari |
* @param genes |
2 |
26 Feb 07 |
jari |
474 |
*/ |
2 |
26 Feb 07 |
jari |
475 |
private void onSave( double[] gamma1, double[] gamma2, String[] genes) { |
2 |
26 Feb 07 |
jari |
476 |
String currentPath = TMEV.getDataPath(); |
2 |
26 Feb 07 |
jari |
477 |
RamaTextFileFilter textFilter = new RamaTextFileFilter(); |
2 |
26 Feb 07 |
jari |
478 |
JFileChooser chooser = new JFileChooser(currentPath); |
2 |
26 Feb 07 |
jari |
479 |
chooser.addChoosableFileFilter(textFilter); |
2 |
26 Feb 07 |
jari |
480 |
if( chooser.showSaveDialog(new JFrame()) == JFileChooser.APPROVE_OPTION ) { |
2 |
26 Feb 07 |
jari |
481 |
File saveFile; |
2 |
26 Feb 07 |
jari |
482 |
|
2 |
26 Feb 07 |
jari |
483 |
if( chooser.getFileFilter() == textFilter ) { |
2 |
26 Feb 07 |
jari |
//make sure to add .txt |
2 |
26 Feb 07 |
jari |
485 |
String path = chooser.getSelectedFile().getPath(); |
2 |
26 Feb 07 |
jari |
486 |
if( path.toLowerCase().endsWith("txt") ) { |
2 |
26 Feb 07 |
jari |
//great, already ok |
2 |
26 Feb 07 |
jari |
488 |
saveFile = new File(path); |
2 |
26 Feb 07 |
jari |
489 |
} else { |
2 |
26 Feb 07 |
jari |
//add it |
2 |
26 Feb 07 |
jari |
491 |
String subPath; |
2 |
26 Feb 07 |
jari |
492 |
int period = path.lastIndexOf("."); |
2 |
26 Feb 07 |
jari |
493 |
if( period != -1 ) { |
2 |
26 Feb 07 |
jari |
494 |
System.out.println("period = -1"); |
2 |
26 Feb 07 |
jari |
495 |
subPath = path.substring(0, period); |
2 |
26 Feb 07 |
jari |
496 |
} else { |
2 |
26 Feb 07 |
jari |
497 |
subPath = path; |
2 |
26 Feb 07 |
jari |
498 |
} |
2 |
26 Feb 07 |
jari |
499 |
String newPath = subPath + ".txt"; |
2 |
26 Feb 07 |
jari |
500 |
saveFile = new File(newPath); |
2 |
26 Feb 07 |
jari |
501 |
} |
2 |
26 Feb 07 |
jari |
502 |
} else { |
2 |
26 Feb 07 |
jari |
503 |
saveFile = chooser.getSelectedFile(); |
2 |
26 Feb 07 |
jari |
504 |
} |
2 |
26 Feb 07 |
jari |
505 |
StringBuffer sb = new StringBuffer(); |
2 |
26 Feb 07 |
jari |
506 |
sb.append( "GeneName" ); |
2 |
26 Feb 07 |
jari |
507 |
sb.append( BridgeGUI.TAB ); |
2 |
26 Feb 07 |
jari |
508 |
sb.append( "RatioA" ); |
2 |
26 Feb 07 |
jari |
509 |
sb.append( BridgeGUI.TAB ); |
2 |
26 Feb 07 |
jari |
510 |
sb.append( "RatioB" ); |
2 |
26 Feb 07 |
jari |
511 |
sb.append( BridgeGUI.END_LINE ); |
2 |
26 Feb 07 |
jari |
512 |
|
2 |
26 Feb 07 |
jari |
513 |
for( int i = 0; i < gamma1.length; i++ ) { |
2 |
26 Feb 07 |
jari |
514 |
sb.append( genes[ i ] ); |
2 |
26 Feb 07 |
jari |
515 |
sb.append( BridgeGUI.TAB ); |
2 |
26 Feb 07 |
jari |
516 |
sb.append( gamma1[ i ] ); |
2 |
26 Feb 07 |
jari |
517 |
sb.append( BridgeGUI.TAB ); |
2 |
26 Feb 07 |
jari |
518 |
sb.append( gamma2[ i ] ); |
2 |
26 Feb 07 |
jari |
519 |
sb.append( BridgeGUI.END_LINE ); |
2 |
26 Feb 07 |
jari |
520 |
} |
2 |
26 Feb 07 |
jari |
521 |
|
2 |
26 Feb 07 |
jari |
522 |
this.writeFile(saveFile, sb.toString()); |
2 |
26 Feb 07 |
jari |
523 |
|
2 |
26 Feb 07 |
jari |
//looks like it all went ok, save path |
2 |
26 Feb 07 |
jari |
525 |
this.updateDataPath( saveFile.getAbsolutePath() ); |
2 |
26 Feb 07 |
jari |
526 |
} else { |
2 |
26 Feb 07 |
jari |
//System.out.println("User cancelled Gene List Save"); |
2 |
26 Feb 07 |
jari |
528 |
} |
2 |
26 Feb 07 |
jari |
529 |
}//onSaveGeneList() |
2 |
26 Feb 07 |
jari |
530 |
|
2 |
26 Feb 07 |
jari |
531 |
|
2 |
26 Feb 07 |
jari |
532 |
private void updateDataPath(String dataPath) { |
2 |
26 Feb 07 |
jari |
533 |
if (dataPath == null) |
2 |
26 Feb 07 |
jari |
534 |
return; |
2 |
26 Feb 07 |
jari |
535 |
String renderedSep = "/"; |
2 |
26 Feb 07 |
jari |
536 |
String renderedPath = new String(); |
2 |
26 Feb 07 |
jari |
537 |
|
2 |
26 Feb 07 |
jari |
538 |
String sep = System.getProperty("file.separator"); |
2 |
26 Feb 07 |
jari |
539 |
String lineSep = System.getProperty("line.separator"); |
2 |
26 Feb 07 |
jari |
540 |
|
2 |
26 Feb 07 |
jari |
541 |
StringTokenizer stok = new StringTokenizer(dataPath, sep); |
2 |
26 Feb 07 |
jari |
542 |
|
2 |
26 Feb 07 |
jari |
543 |
this.dataPath = new String(); |
2 |
26 Feb 07 |
jari |
544 |
|
2 |
26 Feb 07 |
jari |
545 |
String str; |
2 |
26 Feb 07 |
jari |
546 |
while (stok.hasMoreTokens() && stok.countTokens() > 1) { |
2 |
26 Feb 07 |
jari |
547 |
str = stok.nextToken(); |
2 |
26 Feb 07 |
jari |
548 |
renderedPath += str + renderedSep; |
2 |
26 Feb 07 |
jari |
549 |
this.dataPath += str + sep; |
2 |
26 Feb 07 |
jari |
550 |
} |
2 |
26 Feb 07 |
jari |
// sets the data path in config to render well |
2 |
26 Feb 07 |
jari |
552 |
TMEV.updateDataPath(renderedPath); |
2 |
26 Feb 07 |
jari |
553 |
|
2 |
26 Feb 07 |
jari |
// sets variable to conform to OS spec. |
2 |
26 Feb 07 |
jari |
555 |
TMEV.setDataPath(this.dataPath); |
2 |
26 Feb 07 |
jari |
556 |
} |
2 |
26 Feb 07 |
jari |
557 |
|
2 |
26 Feb 07 |
jari |
558 |
|
2 |
26 Feb 07 |
jari |
559 |
/** |
2 |
26 Feb 07 |
jari |
* Write the String s to File f |
2 |
26 Feb 07 |
jari |
561 |
* |
2 |
26 Feb 07 |
jari |
* @param f |
2 |
26 Feb 07 |
jari |
* @param s |
2 |
26 Feb 07 |
jari |
564 |
*/ |
2 |
26 Feb 07 |
jari |
565 |
private void writeFile(File f, String s) { |
2 |
26 Feb 07 |
jari |
566 |
try { |
2 |
26 Feb 07 |
jari |
567 |
FileWriter fw = new FileWriter(f); |
2 |
26 Feb 07 |
jari |
568 |
fw.write(s); |
2 |
26 Feb 07 |
jari |
569 |
fw.flush(); |
2 |
26 Feb 07 |
jari |
570 |
fw.close(); |
2 |
26 Feb 07 |
jari |
571 |
} catch( IOException e ) { |
2 |
26 Feb 07 |
jari |
572 |
e.printStackTrace(); |
2 |
26 Feb 07 |
jari |
573 |
} |
2 |
26 Feb 07 |
jari |
574 |
}//writeFile() |
2 |
26 Feb 07 |
jari |
575 |
|
2 |
26 Feb 07 |
jari |
576 |
|
2 |
26 Feb 07 |
jari |
577 |
/** |
2 |
26 Feb 07 |
jari |
* Just un Log transforms a double array by base |
2 |
26 Feb 07 |
jari |
* @param log |
2 |
26 Feb 07 |
jari |
* @param base |
2 |
26 Feb 07 |
jari |
* @return |
2 |
26 Feb 07 |
jari |
582 |
*/ |
2 |
26 Feb 07 |
jari |
583 |
private double[] unLogify( double[] log, int base ) { |
2 |
26 Feb 07 |
jari |
584 |
double[] toReturn = new double[ log.length ]; |
2 |
26 Feb 07 |
jari |
585 |
|
2 |
26 Feb 07 |
jari |
586 |
for( int i = 0; i < log.length; i ++ ) { |
2 |
26 Feb 07 |
jari |
587 |
double d = log[ i ]; |
2 |
26 Feb 07 |
jari |
588 |
double y = Math.pow( 2, d ); |
2 |
26 Feb 07 |
jari |
589 |
toReturn[ i ] = y; |
2 |
26 Feb 07 |
jari |
590 |
} |
2 |
26 Feb 07 |
jari |
591 |
|
2 |
26 Feb 07 |
jari |
592 |
return toReturn; |
2 |
26 Feb 07 |
jari |
593 |
}//unLogify() |
2 |
26 Feb 07 |
jari |
594 |
|
2 |
26 Feb 07 |
jari |
595 |
|
2 |
26 Feb 07 |
jari |
596 |
/** |
2 |
26 Feb 07 |
jari |
* Takes a connection string in the form ipaddress:port# and returns just the |
2 |
26 Feb 07 |
jari |
* port number part |
2 |
26 Feb 07 |
jari |
* @param connPort |
2 |
26 Feb 07 |
jari |
* @return |
2 |
26 Feb 07 |
jari |
601 |
*/ |
2 |
26 Feb 07 |
jari |
602 |
private int parseIPort( String connPort ) { |
2 |
26 Feb 07 |
jari |
603 |
if( connPort == null ) { |
2 |
26 Feb 07 |
jari |
604 |
return 6311; |
2 |
26 Feb 07 |
jari |
605 |
} else { |
2 |
26 Feb 07 |
jari |
606 |
int iColon = connPort.indexOf( ":" ); |
2 |
26 Feb 07 |
jari |
607 |
if( iColon == -1 ) { |
2 |
26 Feb 07 |
jari |
608 |
return 6311; |
2 |
26 Feb 07 |
jari |
609 |
} else { |
2 |
26 Feb 07 |
jari |
610 |
int toReturn = Integer.parseInt( connPort.substring( iColon + 1 ) ); |
2 |
26 Feb 07 |
jari |
611 |
return toReturn; |
2 |
26 Feb 07 |
jari |
612 |
} |
2 |
26 Feb 07 |
jari |
613 |
} |
2 |
26 Feb 07 |
jari |
614 |
} |
2 |
26 Feb 07 |
jari |
615 |
/** |
2 |
26 Feb 07 |
jari |
* Takes a connection string in the form ipaddress:port# and returns just the |
2 |
26 Feb 07 |
jari |
* ipaddress part |
2 |
26 Feb 07 |
jari |
* @param connPort |
2 |
26 Feb 07 |
jari |
* @return |
2 |
26 Feb 07 |
jari |
620 |
*/ |
2 |
26 Feb 07 |
jari |
621 |
private String parseSPort( String connPort ) { |
2 |
26 Feb 07 |
jari |
622 |
if( connPort == null ) { |
2 |
26 Feb 07 |
jari |
623 |
return "127.0.0.1"; |
2 |
26 Feb 07 |
jari |
624 |
} else { |
2 |
26 Feb 07 |
jari |
625 |
int iColon = connPort.indexOf( ":" ); |
2 |
26 Feb 07 |
jari |
626 |
if( iColon == -1 ) { |
2 |
26 Feb 07 |
jari |
627 |
return "127.0.0.1"; |
2 |
26 Feb 07 |
jari |
628 |
} else { |
2 |
26 Feb 07 |
jari |
629 |
return connPort.substring( 0, iColon ); |
2 |
26 Feb 07 |
jari |
630 |
} |
2 |
26 Feb 07 |
jari |
631 |
} |
2 |
26 Feb 07 |
jari |
632 |
} |
2 |
26 Feb 07 |
jari |
633 |
|
2 |
26 Feb 07 |
jari |
634 |
|
2 |
26 Feb 07 |
jari |
635 |
/** |
2 |
26 Feb 07 |
jari |
* Displays an error dialog |
2 |
26 Feb 07 |
jari |
* @param message |
2 |
26 Feb 07 |
jari |
638 |
*/ |
2 |
26 Feb 07 |
jari |
639 |
public void error( String message ) { |
2 |
26 Feb 07 |
jari |
640 |
JOptionPane.showMessageDialog( new JFrame(), |
2 |
26 Feb 07 |
jari |
641 |
message, "Input Error", JOptionPane.ERROR_MESSAGE ); |
2 |
26 Feb 07 |
jari |
642 |
}//end error() |
2 |
26 Feb 07 |
jari |
643 |
|
2 |
26 Feb 07 |
jari |
644 |
|
2 |
26 Feb 07 |
jari |
645 |
public void setYNum( String s ) { |
2 |
26 Feb 07 |
jari |
646 |
this.yNum = s; |
2 |
26 Feb 07 |
jari |
647 |
} |
2 |
26 Feb 07 |
jari |
648 |
public void setYDenom( String s ) { |
2 |
26 Feb 07 |
jari |
649 |
this.yDenom = s; |
2 |
26 Feb 07 |
jari |
650 |
} |
2 |
26 Feb 07 |
jari |
651 |
}//end class |
2 |
26 Feb 07 |
jari |
652 |
/* |
2 |
26 Feb 07 |
jari |
653 |
|
2 |
26 Feb 07 |
jari |
654 |
|
2 |
26 Feb 07 |
jari |
private String BridgeNonSwapString( IData data, Vector vBridgeHyb ) { |
2 |
26 Feb 07 |
jari |
StringBuffer sbTreat = new StringBuffer( BridgeGUI.R_VECTOR_NAME + " <- c(" ); |
2 |
26 Feb 07 |
jari |
StringBuffer sbControl = new StringBuffer(); |
2 |
26 Feb 07 |
jari |
658 |
|
2 |
26 Feb 07 |
jari |
//figure out which color is treated, which is control |
2 |
26 Feb 07 |
jari |
BridgeHyb firstHyb = ( BridgeHyb ) vBridgeHyb.elementAt( 0 ); |
2 |
26 Feb 07 |
jari |
boolean controlCy3 = firstHyb.controlCy3(); |
2 |
26 Feb 07 |
jari |
662 |
|
2 |
26 Feb 07 |
jari |
//loop through all the hybs |
2 |
26 Feb 07 |
jari |
for( int i = 0; i < vBridgeHyb.size(); i ++ ) { |
2 |
26 Feb 07 |
jari |
if( i > 0 ) { |
2 |
26 Feb 07 |
jari |
sbTreat.append( "," ); |
2 |
26 Feb 07 |
jari |
sbControl.append( "," ); |
2 |
26 Feb 07 |
jari |
668 |
} |
2 |
26 Feb 07 |
jari |
669 |
|
2 |
26 Feb 07 |
jari |
BridgeHyb hyb = ( BridgeHyb ) vBridgeHyb.elementAt( i ); |
2 |
26 Feb 07 |
jari |
int iHyb = hyb.getHybIndex(); |
2 |
26 Feb 07 |
jari |
672 |
|
2 |
26 Feb 07 |
jari |
//loop through the genes |
2 |
26 Feb 07 |
jari |
int iGene = data.getExperiment().getNumberOfGenes(); |
2 |
26 Feb 07 |
jari |
for( int g = 0; g < iGene; g ++ ) { |
2 |
26 Feb 07 |
jari |
if( g > 0 ) { |
2 |
26 Feb 07 |
jari |
sbTreat.append( "," ); |
2 |
26 Feb 07 |
jari |
sbControl.append( "," ); |
2 |
26 Feb 07 |
jari |
679 |
} |
2 |
26 Feb 07 |
jari |
680 |
|
2 |
26 Feb 07 |
jari |
float cy5 = data.getCY5( iHyb, g ); |
2 |
26 Feb 07 |
jari |
float cy3 = data.getCY3( iHyb, g ); |
2 |
26 Feb 07 |
jari |
683 |
|
2 |
26 Feb 07 |
jari |
if( controlCy3 ) { |
2 |
26 Feb 07 |
jari |
//treated is Cy5 for all hybs since they're all the same |
2 |
26 Feb 07 |
jari |
//sbTreat.append( data.getCY5( iHyb, g ) ); |
2 |
26 Feb 07 |
jari |
//sbControl.append( data.getCY3( iHyb, g ) ); |
2 |
26 Feb 07 |
jari |
sbTreat.append( cy5 ); |
2 |
26 Feb 07 |
jari |
sbTreat.append( cy3 ); |
2 |
26 Feb 07 |
jari |
//System.out.println( i + "," + g + ":" + data.getCY5( iHyb, g ) ); |
2 |
26 Feb 07 |
jari |
} else { |
2 |
26 Feb 07 |
jari |
//treated is Cy3 for all hybs since they're all the same |
2 |
26 Feb 07 |
jari |
//sbTreat.append( data.getCY3( iHyb, g ) ); |
2 |
26 Feb 07 |
jari |
//sbControl.append( data.getCY5( iHyb, g ) ); |
2 |
26 Feb 07 |
jari |
sbTreat.append( cy3 ); |
2 |
26 Feb 07 |
jari |
sbTreat.append( cy5 ); |
2 |
26 Feb 07 |
jari |
//System.out.println( i + "," + g + ":" + data.getCY3( iHyb, g ) ); |
2 |
26 Feb 07 |
jari |
698 |
} |
2 |
26 Feb 07 |
jari |
}//g |
2 |
26 Feb 07 |
jari |
}//i |
2 |
26 Feb 07 |
jari |
701 |
|
2 |
26 Feb 07 |
jari |
sbTreat.append( "," ); |
2 |
26 Feb 07 |
jari |
sbTreat.append( sbControl ); |
2 |
26 Feb 07 |
jari |
sbTreat.append( ")" ); |
2 |
26 Feb 07 |
jari |
705 |
|
2 |
26 Feb 07 |
jari |
return sbTreat.toString(); |
2 |
26 Feb 07 |
jari |
}//BridgeNonSwapString() |
2 |
26 Feb 07 |
jari |
//flip doesn't matter for bridge |
2 |
26 Feb 07 |
jari |
String sData = this.BridgeNonSwapString( data, bhs.getVHyb() ); |
2 |
26 Feb 07 |
jari |
int iGene = data.getExperiment().getNumberOfGenes(); |
2 |
26 Feb 07 |
jari |
int nbCol1 = 0; |
2 |
26 Feb 07 |
jari |
int iHybKount = bhs.getVHyb().size(); |
2 |
26 Feb 07 |
jari |
int iColorKount = iHybKount * 2; |
2 |
26 Feb 07 |
jari |
int iOne = iHybKount; |
2 |
26 Feb 07 |
jari |
int iTwo = iHybKount + 1; |
2 |
26 Feb 07 |
jari |
716 |
*/ |
2 |
26 Feb 07 |
jari |
717 |
/* |
2 |
26 Feb 07 |
jari |
//should clear R |
2 |
26 Feb 07 |
jari |
rc.voidEval( "rm(" + BridgeGUI.R_VECTOR_NAME + " )" ); |
2 |
26 Feb 07 |
jari |
720 |
|
2 |
26 Feb 07 |
jari |
//load rama |
2 |
26 Feb 07 |
jari |
rc.voidEval( "library(bridge)" ); |
2 |
26 Feb 07 |
jari |
723 |
|
2 |
26 Feb 07 |
jari |
//load data as vector |
2 |
26 Feb 07 |
jari |
rc.voidEval( sData ); |
2 |
26 Feb 07 |
jari |
726 |
|
2 |
26 Feb 07 |
jari |
//reform vector data into matrix |
2 |
26 Feb 07 |
jari |
rc.voidEval( "dim(" + BridgeGUI.R_VECTOR_NAME + ") <- c(" + iGene + "," |
2 |
26 Feb 07 |
jari |
+ iColorKount + ")" ); |
2 |
26 Feb 07 |
jari |
730 |
|
2 |
26 Feb 07 |
jari |
731 |
|
2 |
26 Feb 07 |
jari |
//call fit.model() |
2 |
26 Feb 07 |
jari |
rc.voidEval( this.createMcMc( iGene, iHybKount, iOne, iTwo, |
2 |
26 Feb 07 |
jari |
iColorKount, B, minIter, dataType ) ); |
2 |
26 Feb 07 |
jari |
735 |
|
2 |
26 Feb 07 |
jari |
rc.voidEval( "gamma1<-mat.mean(mcmc.hiv$gamma1)[,1]" ); |
2 |
26 Feb 07 |
jari |
rc.voidEval( "gamma2<-mat.mean(mcmc.hiv$gamma2)[,1]" ); |
2 |
26 Feb 07 |
jari |
738 |
|
2 |
26 Feb 07 |
jari |
//get normalized data vectors |
2 |
26 Feb 07 |
jari |
double[] gamma1 = rc.eval( "gamma1" ).asDoubleArray(); |
2 |
26 Feb 07 |
jari |
double[] gamma2 = rc.eval( "gamma2" ).asDoubleArray(); |
2 |
26 Feb 07 |
jari |
double[] pprob = rc.eval( "mcmc.hiv$post.p" ).asDoubleArray(); |
2 |
26 Feb 07 |
jari |
743 |
*/ |