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<body bgcolor = "#FFFFCC"><basefont face = "Arial"> |
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<h1>PTM: Pavlidis Template Matching</h1><h2>Parameter Information</h2> |
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<hr size = 10> |
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<h2>Template Selection Tabs</h2> |
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The five tabbed panels at the top of the dialog select to view candidate templates |
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from various sources. |
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The Gene Template tab provides a list of genes in the data set and their expression |
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profile graphs. Selection of elements in the list display the expression pattern for |
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that gene. |
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The Gene Cluster Template tab provides a list and view of templates which are the |
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mean values of stored (colored) clusters. |
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The Experiment Template, and Experiment Cluster Template tabs provide the same |
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functionality but use experiment templates. |
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The Saved Template tab provides an interface for loading gene and |
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experiment templates. Templates loaded from files will populate a list from |
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which a template may be selected. |
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A button in each of these areas is used to select the displayed template for |
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matching. |
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<br> |
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<h2>Threshold Parameters</h2> |
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<h3>Use Absolute R</h3> |
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Using this option will select expression patterns that are either positively |
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or negatively correlated with the template. |
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<h3>Use Threshold R</h3> |
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This option will indicate that the threshold value for determining a match is |
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the R value between the expression vector and the template. |
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<h3>Use Threshold p-Value</h3> |
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This option will indicate that the threshold value for determining a match is |
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the p value on R between the expression vector and the template. |
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<h3>Threshold Input Value</h3> |
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This is either a supplied value for R or a p-value ranging from 0.0 to 1.0. |
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R values closer to 1.0 are more stringent. p-values closer to 0 are more stringent. |
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<h2>Save Template</h2> |
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This button launches a file browser to allow the user to save the current template |
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to a tab delimited text file. These files can be loaded from the Saved Template tab |
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interface. |
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<h2> Hierarchical Clustering </h2> |
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This check box selects whether to perform hierarchical clustering on the elements in the |
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resulting matched and unmatched element sets. |
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<br> |
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</basefont> |
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</body> |
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</html> |