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<body bgcolor = "#FFFFCC"><basefont face = "Arial"> |
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<h1>QTC: QT_Cluster</h1><h2>Parameter Information</h2> |
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<hr size = 10> |
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<h2> Sample Selection </h2> |
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The sample selection option indicates whether to cluster genes or experiments. |
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<h2> Distance Metric Selection </h2> |
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This area allows the selection of the metric to be used to assess gene-to-gene |
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or sample-to-sample distances. The initial metric displayed (choosen) corresponds to the global |
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setting in the Multiple Array Viewer's 'Metrics' menu. Alterations to the |
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chosen metric in this dialog will only alter the metric used for the current |
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algorithm run. The global setting in the main 'Metrics' menu will remain unchanged. |
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<br><br> |
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An appendix in the MeV manual describes the distance metrics offered in MeV. |
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<h2>Maximum Cluster Diameter</h2> |
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Cluster Diameter is related to the overall variability between the member elements |
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within a cluster. Maximum Cluster Diameter is a constraint on that variance such that all |
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formed clusters must have a diameter (variability) smaller that the entered maximum. |
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Increasing the maximum diameter tends to make larger and more variable clusters and |
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decreasing the maximum diameter tends to produce smaller less variable clusters. |
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<br> |
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<h2>Minimum Cluster Population</h2> |
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The minimum number of elements required to be present in order to |
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form a cluster. For instance a Minimum Cluster Population of 10 |
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insures that all formed clusters will have at least 10 members. |
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<br> |
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<h2> Hierarchical Clustering </h2> |
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This check box selects whether to perform hierarchical clustering on the elements in each cluster |
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created. |
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</basefont> |
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</body> |
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</html> |